Comité utilisateurs et Publications



Comité utilisateurs

Le comité utilisateurs de CISA (Plateforme de Cytométrie et Plateforme d'Imagerie) se réunie une fois par an. Il est constitué de la responsable scientifique et des responsables opérationnels, d'un représentant de chaque équipe du Centre de Recherche Saint-Antoine (CRSA).


Réunion 13 novembre 2015

Réunion 03 mai 2016

Réunion 29 septembre 2016

Réunion 10 mai 2017

Réunion 15 novembre 2017

Réunion 04 avril 2018
Réunion 20 février 2019
Réunion 01 octobre 2020
Réunion 18 janvier 2022
Publications 2014

A subset of bone marrow stromal cells regulate ATP-binding cassette gene expression via insulin-like growth factor-I in a leukemia cell line.

Benabbou N, Mirshahi P, Bordu C, Faussat AM, Tang R, Therwath A, Soria J, Marie JP, Mirshahi M.

Int J Oncol. 2014 Oct;45(4):1372-80.


Predictive markers of clinical outcome in the GRMD dog model of Duchenne Muscular Dystrophy.

Barthélémy I, Pinto-Mariz F, Yada E, Desquilbet L, Savino W, Silva-Barbosa SD, Faussat AM, Mouly V, Voit T, Blot S, Butler-Browne G.

Dis Model Mech. 2014 Sep 26.


Loss of WISP2/CCN5 in Estrogen-Dependent MCF7 Human Breast Cancer Cells Promotes a Stem-Like Cell Phenotype.

Nathalie Ferrand,Anne Gnanapragasam,Guillaume Dorothee,Gérard Redeuilh,Annette K. Larsen,and Michèle Sabbah.
PLoS One. 2014; 9(2): e87878.


Publications 2015

Molecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells

Shaghayegh Rouzbeh, Ladan Kobari, Marie Cambot, Christelle Mazurier, Nicolas Hebert, Anne-Marie Faussat, Charles Durand, Luc Douay and Hélène Lapillonne

Stem Cells. 2015 Aug;33(8):2431-41


Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism

M Pilorge, C Fassier, H Le Corronc, A Potey, J Bai, S De Gois, E Delaby, B Assouline, V Guinchat, F Devillard, R Delorme, G Nygren, M Råstam, JC Meier, S Otani H Cheval, VM James, M Topf, TN Dear, C Gillberg, M Leboyer, B Giros, S Gautron, J Hazan1, RJ Harvey, P Legendre and C Betancur.

Molecular Psychiatry. (2015), 1 – 10


Mutations of the Imprinted CDKN1C Gene as a Cause of the Overgrowth Beckwith-Wiedemann Syndrome: Clinical Spectrum and Functional Characterization.

Brioude F, Netchine I, Praz F, Le Jule M, Calmel C, Lacombe D, Edery P, Catala M, Odent S, Isidor B, Lyonnet S, Sigaudy S, Leheup B, Audebert-Bellanger S, Burglen L, Giuliano F, Alessandri JL, Cormier-Daire V, Laffargue F, Blesson S, Coupier I, Lespinasse J, Blanchet P, Boute O, Baumann C, Polak M, Doray B, Verloes A, Viot G, Le Bouc Y, Rossignol S.

Hum Mutat. 2015 Sep;36(9):894-902.


Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration.

Hu SJ, Calippe B, Lavalette S, Roubeix C, Montassar F, Housset M, Levy O, Delarasse C, Paques M, Sahel JA, Sennlaub F, Guillonneau X.

J Neurosci. 2015 May 6;35(18):6987-96.


Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitorsMeriam Ayadi,Anaïs Bouygues,Djamila Ouaret, Nathalie Ferrand,Salem Chouaib, Jean-Paul Thiery,Christian Muchardt, Michèle Sabbah, and Annette K Larsenn.
Oncotarget. 2015 Jul 30; 6(21): 18518–18533.



Communication dans des actes de congrés

FASS and FAST-FIN, two new FACS based methods for the purification of brain tissue organelles after subcellular fractionations.

Annie Munier, Elisa Luquet, Etienne Herzog, Lucile Marion-Poll, Enrica Montalban, Denis Hervé, Jean-Antoine Girault.

Cyto 2015 :26 juin - 1 juillet. Glasgow.pdf


Publications 2016

Delayed Healing of Sickle Cell Ulcers Is due to Impaired Angiogenesis and CXCL12 Secretion in Skin Wounds.

Nguyen VT1, Nassar D2, Batteux F3, Raymond K4, Tharaux PL5, Aractingi S6.

J Invest Dermatol. 2016 Feb;136(2):497-506.


Regulatory T cells delay disease progression in Alzheimer-like pathology.

Dansokho C1, Ait Ahmed D1, Aid S2, Toly-Ndour C3, Chaigneau T3, Calle V3, Cagnard N4, Holzenberger M5, Piaggio E6, Aucouturier P3, Dorothée G3.

Brain. 2016 Apr;139(Pt 4):1237-51.


NOV/CCN3: A New Adipocytokine Involved in Obesity-Associated Insulin Resistance.

Martinerie C1, Garcia M1, Do TT1, Antoine B1, Moldes M1, Dorothee G2, Kazazian C1, Auclair M1, Buyse M3, Ledent T2, Marchal PO1, Fesatidou M1, Beisseiche A4, Koseki H5, Hiraoka S6, Chadjichristos CE7, Blondeau B4, Denis RG8, Luquet S8, Fève B9.

Diabetes. 2016 Sep;65(9):2502-15.

Publications 2017

Ccl2/Ccr2 signalling recruits a distinct fetal microchimeric population that rescues delayed maternal wound healing

Mathieu Castela,1,2 Dany Nassar,3,4,* Maria Sbeih,1,2,* Marie Jachiet,1,2,3 Zhe Wang,1,† and Selim Aractingia,1,3,5,†

Nat Commun. 2017; 8: 15463.


Thrombopoietin Secretion by Human Ovarian Cancer Cells.

Besbes S1,2, Shah S1, Al-Dybiat I1, Mirshahi S3, Helfer H1, Najah H1, Fourgeaud C1, Pocard M1, Ghedira I2, Soria J1, Mirshahi M1.
Int J Cell Biol. 2017;2017:1873834.

Igf1r signalling acts on the anagen-to-catagen transition in the hair cycle.

Castela M1,2, Linay F1,2, Roy E1,2,3, Moguelet P4, Xu J1,2, Holzenberger M1,2, Khosrotehrani K3, Aractingi S1,5,6.
Exp Dermatol. 2017 Sep;26(9):785-791.

P-Body Purification Reveals the Condensation of Repressed mRNA Regulons.

Hubstenberger A1, Courel M2, Bénard M2, Souquere S3, Ernoult-Lange M2, Chouaib R4, Yi Z2, Morlot JB5, Munier A6, Fradet M7, Daunesse M8, Bertrand E9, Pierron G3, Mozziconacci J5, Kress M2, Weil D10.
Mol Cell. 2017 Oct 5;68(1):144-157
Publications 2018

Neutrophil hyperactivation correlates with Alzheimer's disease progression.

Dong Y, Lagarde J, Xicota L, Corne H, Chantran Y, Chaigneau T, Crestani B, Bottlaender M, Potier MC, Aucouturier P, Dorothée G, Sarazin M, Elbim C.
Ann Neurol. 2018 Feb;83(2):387-405. 

Quantitative and functional alterations of 6-sulfo LacNac dendritic cells in multiple myeloma.

Lamarthée B, de Vassoigne F, Malard F, Stocker N, Boussen I, Médiavilla C, Tang R, Fava F, Garderet L, Marjanovic Z, Brissot E, Mohty M, Gaugler B.

Oncoimmunology. 2018 Mar 19;7(7). 


Discontinuous Schedule of Bevacizumab in Colorectal Cancer Induces Accelerated Tumor Growth and Phenotypic Changes
Becherirat S, Valamanesh F, Karimi M, Faussat AM, Launay JM,Pimpie C, Therwath A and Pocard M.
Transl Oncol. 2018 Apr;11(2):406-415

AβPP-induced UPR Transcriptomic Signature of Glial Cells to Oxidative Stress as an Adaptive Mechanism to Preserve Cell Function and Survival

Chalour N , Maoui A, Rat P, Massicot F, Dutot M, Faussat AM, Devevre E, Limb A, Warnet JM, Treton J, Dinet V, Mascarelli F.

Curr Alzheimer Res. 2018;15(7):643-654


Identification of Positively and Negatively Selected Driver Gene Mutations Associated With Colorectal Cancer With Microsatellite Instability.

Jonchere V, Marisa L, Greene M, Virouleau A, Buhard O, Bertrand R, Svrcek M, Cervera P, Goloudina A, Guillerm E, Coulet F, Landman S, Ratovomanana T, Job S, Ayadi M, Elarouci N, Armenoult L, Merabtene F, Dumont S, Parc Y, Lefèvre JH, André T, Fléjou JF Guilloux A, Collura A, de Reyniès A, Duval A.

Cell Mol Gastroenterol Hepatol. 2018 Jun 13;6(3):277-300.


Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability.

Bokhari A, Jonchere V, Lagrange A, Bertrand R, Svrcek M, Marisa L, Buhard O, Greene M, Demidova A, Jia J, Adriaenssens E, Chassat T, Biard DS, Flejou JF, Lejeune F Duval A, Collura A.

Oncogenesis. 2018 Sep 19;7(9):70.



Publications 2019

Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure

Dalle H, Garcia M, Antoine B, Boehm V, Huong Do TT, Buyse M, Ledent T, Lamazière A, Magnan C, Postic C, Denis GR, Luquet S, Fève B and Moldes M.

Diabetes 2019 Feb; 68(2): 305-317.


Insulin receptor isoform A favors tumor progression in human hepatocellular carcinoma by increasing stem/progenitor cell features.

Benabou E, Salamé Z, Wendum D, Lequoy M, Tahraoui S, Merabtene F, Chrétien Y, Scatton O, Rosmorduc O, Fouassier L, Fartoux L, Praz F, Desbois-Mouthon C.

Cancer Lett. 2019 May 28;450:155-168.


Methylation Tolerance-Based Functional Assay to Assess Variants of Unknown Significance in the MLH1 and MSH2 Genes and Identify Patients With Lynch Syndrome.

Bouvet D, Bodo S, Munier A, Guillerm E, Bertrand R, Colas C, Duval A, Coulet F, Muleris M.

Gastroenterology. 2019 Aug;157(2):421-431.


Breast-Associated Adipocytes Secretome Induce Fatty Acid Uptake and Invasiveness in Breast Cancer Cells via CD36 Independently of Body Mass Index, Menopausal Status and Mammary Density

Zaoui M, Morel M, Ferrand N, Fellahi S, Bastard J.P, Lamazière A, Kragh Larsen A, Béréziat V, Atlan M and  Sabbah M.

Cancers (Basel). 2019 Dec 13;11(12):2012


Harmful neutrophil subsets in patients with ischemic stroke.

Weisenburger-Lile, D., Dong, Y., Yger, M., Weisenburger, G., Polara, GF., Chaigneau, T., Zapata Ochoa, R., Marro, B., Lapergue, B.,Alamowitch, S. and Elbim, C. 2019. 

Neurol Neuroimmunol Neuroinflamm. 2019 Jul; 6(4): e571. 


Publications 2020

A Far-Red Emitting Fluorescent Chemogenetic Reporter for In Vivo Molecular Imaging

Li C, Tebo A, Thauvin M, Plamont MA, Volovitch M, Morin X, Vriz S, Gautier A.

Angew Chem Int Ed Engl. 2020 Oct 5;59(41):17917-17923.


Cold-Atmospheric Plasma Induces Tumor Cell Deathin Preclinical In Vivo and In Vitro Models ofHuman Cholangiocarcinoma.

Vaquero, J., Judée, F., Vallette, M., Decauchy, H., Arbelaiz, A., Aoudjehane, L., Scatton, O., Gonzalez-Sanchez, E., Merabtene, F., Augustin, J., Housset, C., Dufour, T., and Fouassier, L. 

Cancers 2020,12, 1280; doi:10.3390/cancers12051280 


Insights into the antiproliferative mechanism of (C^N)-chelated half-sandwich iridium complexes†

Ramos R , Zimbron JM , Thorimbert S , Chamoreau LM , Munier A , Botu Iha C , Karaiskou A , Salmain M , Sobczak-Thépot J.

Dalton Trans. 2020 Dec 22;49(48):17635-17641. DOI


Chapitre d’un ouvrage collectif

La cytométrie en flux – 2e édition. Jean-François Mayol, Xavier Ronot, Didier Grunwald (coord.)

Titre du chapitre: Analyse du cycle cellulaire.

Martel-Frachet V., Thomas F., Munier A., Ronot X.




Publications 2021

Orthogonal fluorescent chemogenetic reporters for multicolor imaging

Tebo AG, Moeyaert B, Thauvin M, Carlon-Andres I, Böken D, Volovitch M, Padilla-Parra S, Dedecker P, Vriz S, Gautier A.

Nat Chem Biol. 2021 Jan;17(1):30-38


EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence
Gautheron J, Morisseau C, Chung WC, Zammouri J, Auclair M, Baujat G, Capel E, Moulin C, Wang Y, Yang J, Hammock BD, Cerame B, Phan F, Fève B, Vigouroux C, Andreelli F, Jeru I.

Elife. 2021 Aug 3;10:e68445



Influence of everolimus-based treatment on circulating regulatory T cells after liver transplantation: Comparative study with tacrolimus-based therapy

Barjon C, Dahlqvist G, Ghazal K, Saliba F, Durand F, Duvoux C, Aoudjehane L, Conti F.

Res Hepatol Gastroenterol. 2021 Sep;45(5):101559



Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging

Benaissa H, Ounoughi K, Aujard I, Fischer E, Goïame R, Nguyen J, Tebo AG, Li C, Le Saux T, Bertolin G, Tramier M, Danglot L, Pietrancosta N, Morin X, Jullien L and Gautier A.

Nat Commun. 2021 Nov 30;12(1):6989


Control of Microbial Opsin Expression in Stem Cell Derived Cones for Improved Outcomes in Cell Therapy.

Garita-Hernande, M., Guibal, L., Routet, F., Khabou, H., Riancho, L., Toualbi, L., Picaud, S., Sahel, JA., Goureau, O., Duebel, J and Dalkara, D. 2021. 

Front. Cell. Neurosci., 18 March 2021.



Death rate during the exponential growth of E. coli
Loic Brot, Zengru Di, Romain Morichon, Annie Munier-Godebert, Bertrand Roehner, Joelle Sobczak-Thepot, Angelique Vinit 11 Dec 2021.


Publications 2022

Impairment of neutrophil functions and homeostasis in COVID-19 patients: association with disease severity
Chloé Loyer, Arnaud Lapostolle, Tomas Urbina, Alexandre Elabbadi, Jean-Rémi Lavillegrand, Thomas Chaigneau, Coraly Simoes, Julien Dessajan, Cyrielle Desnos, Mélanie Morin-Brureau, Yannick Chantran, Pierre Aucouturier, Bertrand Guidet, Guillaume Voiriot, Hafid Ait-Oufella, Carole Elbim.

Crit Care. 2022 May 30;26(1):155

Publications 2023

Transinteractome analysis reveals distinct niche requirements for isotype-based plasma cell subsets in the bone marrow
Amélie Bonaud 1 2 , Pierre Larraufie 3 , Mélanie Khamyath 1 2 , Ugo Szachnowski 4 5 , Shaun M Flint 4 , Nadège Brunel-Meunier 6 , François Delhommeau 6 , Annie Munier 7 , Tapio Lönnberg 8 9 , Claire Toffano-Nioche 5 , Daniel Gautheret 5 , Karl Balabanian 1 2 , Marion Espéli 1 2

PMID: 37377335 DOI: 10.1002/eji.202250334


Communication dans des actes de congrés

FAPS a new FACS based method for the purification of membrane-less organelles such as P-bodies

Annie Munier, Angelique Vinit, Adham Safieddine, Dominique Weil.

Cyto 2023 : 20 - 24 juin. Montréal.pdf